Introduction

History
  Korea
  Vietnam

Riot Control Agents
  CS
  DM

Incendiaries
  White Phosphorous
  Napalm

Operation Ranch Hand
  
Mission Overview
  
Defoliants Used
    
 Components
     Agent Orange

   
    
Dioxin
  
   Agent White
      Agent Blue

Ecology

Ambiguities of Vietnam
  Yellow Rain
  Operation Tailwind
  CW Test On Sailors
  Dissenting Warriors

References

Links

 

 

 


YELLOW RAIN

Was biological warfare in the form of mycotoxins used in the Vietnam war? This question has been discussed innumerable times yet no answer has been found.

The basis of the accusations of mycotoxin use came from the United States. The US Secretary of State charged the Soviets of supplying the mycotoxin T2 to their communist allies for military use in South East Asia in 1981 (27). The US claimed that the Soviets had violated the Geneva Protocol and based the accusations on evidence compiled by a US task force (27). The evidence included a single leaf that was recovered from the Thailand/Cambodian border that was covered with mycotoxins in high concentrations (30), and eye witness accounts of Hmong and Cambodian refugees (29). The refugees claimed that air craft dumped a yellow powder over the land that caused unarmed civilians and guerrillas to vomit and involuntarily defecation and resulted in the death of about 7,300 people (29). Analysis of clinical samples of the victims showed that they were exposed to mycotoxins. The finger was pointed at the Soviets because they were the first to discover mycotoxins and their effects when Soviet civilians ate bread baked from flour that contained mold contaminated with mycotoxins (31).

T2 structure
3a,4b,8a-12,13-epoxytrichothec-9-ene-3,4,8,15-
tetrol,4,15-diacetate 8-(3-methylbutanoate) (32)
T2 mycotoxin is also known as trichothecene mycotoxin and is produced by the filamentous fungi Fusarium sporotichiodes-5 (28). T2 is extremely stable to heat (it must be heated at 1500 degree Fahrenheit for 30 minutes to be inactivated) and UV light (28). It is water soluble and alcohol insoluble but when exposed to sodium hypochlorite, T2's toxic activity is destroyed in the environment (29). The molecular weight of T2 is 466.53g/mole and T2 has a melting range of 151-152 degrees Celsius (29).

 

 

 

T2 enters the body through the skin, digestive epithelium, respiratory epithelium, and the eyes. Symptoms of T2 contamination include the following:

TABLE 7: Symptoms of T2 Contamination (28)
fdfd
Skin
Digestive
Respiratory
Eyes
Symptoms
Redness, necrosis and sloughing of epidermis, blistering
Anorexia, nausea, vomiting, watery/bloody diarrhea, cramping
Nose and throat pain, nasal discharge, itching, sneezing, cough, labored breathing, chest pain, and expectoration of blood
Pain, tearing, redness, blurred vision
__(33)

Severe poisoning results in total exhaustion, weakness, loss of muscular coordination, shock and death. Death may occur in minutes, hours, or days depending on the intensity of the exposure (28).

Treatment of T2 exposure is limited. There is no specific antidote, vaccine or chemoprotective pretreatment available (28). Skin may be decontaminated with soap and water, superactive charcoal may be taken if T2 has been swallowed, and eyes may be rinsed with saline (28).

When T2 gets into the body, it effectively inhibits DNA and RNA synthesis, protein synthesis, and mitochondrial functions (29). It also disrupts cell division and cell shape, and reduces hematocrit levels by hemolysis of erythrocytes (29).

The controversy of "Yellow Rain" continues today. Recently, scientists have concluded that yellow rain is actually showers of bee feces from a species of honeybees native to South East Asia (27). The confirmation of the evidence compiled by the US is difficult because the analysis was done for a single sample without controls (29). The Fusarium species naturally occurs in South East Asia, and attacks occurred deep in the jungle (28). Also, the stories of the witnesses have been questioned due to inconsistencies in the accounts (29). No resolution has ever been reached in the case, and this serves as a reminder of how difficult detecting such weapons can be (30).

 

 

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