5,429 B.C.
The House of Jibim Kiba Siber rules the planet Jibet. Their reign will
last 7,000 years [DSN #14].

4,745 B.C.
Omicron Delta IV, the so-called "Shore Leave Planet" or "Amusement Park
Planet" is established by an unknown alien race. A warlike, conquest-
minded offshoot race on Askalon V will perish from the unrestrained use of
the cloning technology in a great war [STM, SL, OUP/a, Log 3, TOS #76].

4,632 B.C.
The Lathanta of 30452 FAS III (Eul Ma'ak Lethantana) develop interplanet-
ary flight and land on 30452 FAS IV (Ma'ak Krannag) intending to exploit
their sister planet's resources. They discover the tribal Krann and
enslave them and their world. Over the following centuries, the Lathanta
strip the resources of Ma'ak Krannag and force the natives to worship them
as gods [TNG #37].

4,630 B.C.
A water gourd archeology item dates from this era, a possession of
Captain Picard in 2370 [TNG #33].

4,250 B.C.
On the planet Vulcan, thousands die of the Skag Maug plague [MRM].

4,032 B.C.
Extraterrestrials abduct a male and a female from Earth. They and their
descendants will be given generations of training to help prevent Earth's
civilization from destroying itself [AE].

3,834 B.C.
Akharin (a.k.a. Flint the Immortal) is born in Mesopotamia on old Earth.
Over the next millenia he will greatly influence Humanity [RM].

Note that "Morgan Lefler" born centuries later on Earth will bear a
very similar longevity problem, though she will be at least in part
Promethian [NF #6].

3,782 B.C.
The Night of Blood: the Krann revolt against the Lathanta, in the 30452
FAS system. Outnumbered on Ma'ak Krannag, the natives rise up and slaugh-
ter their masters with knives. The planet's facilities and industries are
taken over. Although the revolt ends up costing more Krann lives than
Lathanta, the Krann win and, using captured Lathantan ships, carry the war
over to Eul Ma'ak Lethantana. With their economy in ruins, the Lethanta
eventually agree to a peace treaty and pay heavy reparations for their
past exploitation of their world and their people [TNG #37].

3,740 B.C.
Landru, a political figure on UFC 611 (C-111)-Beta III, dies. All his
knowledge lives on in a computer of his own design which will rule
this world for the next six thousand years [RA].

3,725 B.C.
The U.S.S. "Lynx" (NCC-4600) timeship, on her sixth mission, studies
NGC-42583 to prove the Cephid Variable Theory [LTP].

3,632 B.C.
In the 30452 FAS (Ma'ak Terrella) system, planet 3 (Eul Ma'ak Lethantana)
suffers massive thermonuclear bombardment from space by the Krann of
planet 4 (Ma'ak Krannag). The Krann believe the Lethanta to be respons-
ible for introducing an engineered virus on their world tailored to kill
off all higher life forms. The Lethanta are wiped out save for a deep
space colonizing mission of hollowed-out asteroid generation ships
launched some months before this ultimate crisis. The surviving Krann in
space seek revenge by constructing the First Fleet: an interstellar sub-
light expedition to seek out and exterminate the remaining Lethanta. The
Fleet departs for the nearest stars [TNG #37].

3,130 B.C.
The First Fleet of the Krann reaches the nearest star to 30452 FAS. They
settle down on a planet they call Salvation and utilize the natural
resources to build newer and better ships [TNG #37].

3,000 B.C.
All intelligent life in the Beta Portalan system is destroyed by the
Flying Parasites [OA].

The Kalandan Empire is destroyed by a disease organism [TWS, MRM].

2,970 B.C.
The advanced race of beings responsible for the Sagittarian signals die
out due to fading genetic vitality [SFC].

2,750 B.C.
Kohl becomes the Klingon God-patron of medicine on the Klingon homeworld
[MRM].

2,738 B.C.
Apollo, an extraterrestrial humanoid, comes to Earth. He will set the
pattern of the Greek Gods [WM].

2,737 B.C.
Commander Spock and Dr. McCoy are trapped in the Ice Age on the planet
Sarpeidon, having been transported 5,000 years back through time by
the Atavachron. Zarabeth, an exile banished by Zor Khan the Tyrant,
bears Spock's son, Zar [AY, TOS #11].

Zar, in the Lakreo Valley region on Sarpeidon, helps to found society
[TOS #11].

Ginn Donan Garreft Hap Elod Griff Ab Iandor becomes a hero in the Nevis
system (winning his extended name for heroism in battle). He will
eventually agree that the resurrection system creates cold-hearted
fatalists who neither fight nor live anymore [TOS #81].

2,730 B.C.
S'harien becomes known as Vulcan's greatest swordsmith. The U.S.S.
"S'harien" (NCC-3107) class battlecruiser of the 2290s will be named after
him [TOS #18, SfP].

2,718 B.C.
Zarabeth dies in Sarpeidon's Ice Age [TOS #11].

2,712 B.C.
Using the Guardian of Forever, Commander Spock rescues his son, Zar.
Zar is transported to the 23rd Century and later returns to 2,737 B.C.
via the Guardian [TOS #11].

2,700 B.C.
Interstellar war between the Furies and the Unclean draws to an end in
the Alpha Quadrant. Tiin, the Cannibal Whose Bed Would Not Be Shared,
commands the final defense from the Autocrat's chair. A small
fleet of a few thousand ships lures the main contingent of Unclean,
attacking them from out of the black, breaking a four-century truce.
The entire remaining field-unity of Unclean go in pursuit and when
the last Fury ships retreat they number 21 out of more than 4,000.
When the Furies prepare to die, approached by the Unclean from
different vectors, they are thrown through the Bajoran wormhole's
backwash (energy released 5,000 years into the past from c. 2371 A.D.).
Light from the subspace tunneling is so great that it will be
detectable for 3 or 4 millennia. The swarms of the Unclean are
decimated but not annihilated, and they will take up residence
along the eastern spiral arm of the galaxy for the next five
millennia. The defeated Furies civilization (consisting of the Danai,
Bardoi, Ak'lins, Sakill, Jequat, and others) is banished to the far side
of the galaxy. During the first few decades, millions perish while the
civilization falls into barbarism. A thousand year dimness begins.
Their entire culture will be based solely on returning to "Heaven"
(the Alpha Quadrant of the Near Side of the galaxy) from "Hell" (the
Delta Quadrant of the Far Side of the galaxy). Some survivors of this war
in the Alpha Quadrant end up stranded on pre-Federation homeworlds in the
Near Side of the galaxy. These include Earth, Vulcan, Andor, and Orion
among others such as the Klingon homeworlds, and even the Ferengi will
know of them. On Earth, they will form many of the demon legends (in
conjunction with the Danons' visitation?) and the basis of Druidism.
On Vulcan, they are called the Ok'San. The Klingon race will be most
strongly affected (calling them Iraga, Shushara, Hullam'gar, and the
KdIchpon), the demons promising to return with the Havoc and consume the
weak [TOS #79, TNG #41, DSN #16, V #9].

In an alternate timeline, the "Defiant" (from 2371 A.D.) is thrown
back in time to the Furies' final battle by the Unclean's tampering
with the Bajoran wormhole. Lt. Jadzia Dax (just her host body) suffers
lethal radiation exposure and creates a diversion with a lifepod,
allowing the ship to escape. She will be assimilated by the Unclean.
Captain Sisko and the entire ship's complement (save for Lt. Dax's
symbiont and Dr. Bashir) die and the "Defiant" is hidden in a cometary
fragment on the outskirts of Sol system in the Oort cloud. On Year 1,
Day 6, 23:40, Dr. Bashir places the Dax symbiont into stasis. He will
live out the rest of his life in the ship's hull, some 70 years [DSN #16].